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Phages are abundant in the natural world, occurring in seawater, soil, and in humans. They are the natural enemy of bacteria and can help us to control dangerous pathogens

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PHAGE FACTS

  • They are the most abundant microorganisms on the planet
  • Every 48 hours 50% of the entire global bacterial population is replaced by phages
  • Human gut contains one million billion phages (10E15)
  • One ml seawater contains one billion phages
  • Phages are 100 times smaller than bacteria
  • We can not see them under a normal microscope, yet their collective biomass is larger that that of all humans
  • PhageGuard is powered by the natural enemies of bacteria – organic phages.

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Food applications

Phages are proven to be highly effective in killing specific bad bacteria responsible for many of the recurring outbreaks of foodborne illness in the U.S. and around the world.

That kind of specific targeting allows food processors to eliminate Salmonella and Listeria while preserving bacteria beneficial to human health without altering the taste, color, texture or aroma of meats, cheeses or vegetables.

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Human Health

Scientists have known about and studied phages for more than a century. In addition to food safety, phages have been used for decades in medicine to fight infections resistant to antibiotics.

In fact, because drug resistance is an increasingly pressing issue, new therapies with their roots in phage technology have become increasingly important in the field of medical science.

New exiting developments pioneered by Micreos include the world’s first targeted antibacterial products, set to replace antibiotics. The company is viewed as global leader spearheading this exciting new field. With Micreos endolysin technology, for the first time we can kill only the unwanted bacteria – including antibiotic resistant strains – while leaving the beneficial bacteria intact. Endolysins are phage derived enzymes introducing a new 2.0 era for phage therapy. Research shows that the use of endolysins does not induce resistance. This unlocks a completely new approach in dealing with the bacteria around us – also enabling daily use as long as needed while preserving the important biodiversity on our skin and in our gut.

Micreos‘ Staphefekt SA.100 is such an enzyme (endolysin), which kills only Staphylococcus aureus, including MRSA. It is also suitable for routine maintenance therapy, for inflammatory skin conditions such as eczema, rosacea, psoriasis and inflammatory acne.

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Animal health

The overuse of antibiotics in livestock is endangering the availability of antibiotics for humans. Phage based solutions are being develop and tested which can replace these antibiotics in different areas. Feeding phages to live animals can steer and control the gut flora. This will prevent animals from getting sick and reduce or eliminate the use of antibiotics.

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Crop Protection

Phages are essential for life on earth, killing roughly half of all bacteria every two days. They are the most common micro organisms on our planet, present in abundance on our food, skin, in our gut, etc.

Pesticides are widely used in agriculture to control bacterial destruction of fruits and vegetables. Fire blight and potato rot for example can devastate and diminish the harvest. Bacterial resistance to pesticides and the pesticide trap which results in diminishing returns as use is increased time and again, is a trend we need to turn. Phages are being investigated and tested as an alternative natural intervention.

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Future applications

Anywhere specific bacteria pose a problem for society, this platform technology provides new opportunities. Examples are fermentation processes and blue-green algea surface water contamination.